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Suppression of Myc, but not E1a, transformation activity by Max-associated proteins, Mad and Mxi1.

Mad and Mxi1, two members of the Myc-related basic-region helix-loop-helix/leucine-zipper family of proteins, associate directly with Max to form sequence-specific DNA binding heterodimers that are transactivation-incompetent. Mad-Max complexes have been shown to exert a strong repressive effect on...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lahoz, E G, Xu, L, Schreiber-Agus, N, DePinho, R A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1994
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC44024/
https://ncbi.nlm.nih.gov/pubmed/8202517
Tagiau: Ychwanegu Tag
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