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Structure and Mechanistic Implications of a Uroporphyrinogen III Synthase–Product Complex,

Uroporphyrinogen III synthase (U3S) catalyzes the asymmetrical cyclization of a linear tetrapyrrole to form the physiologically relevant uroporphyrinogen III (uro’gen III) isomer during heme biosynthesis. Here, we report four apoenzyme and one product complex crystal structures of the Thermus thermo...

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Bibliografske podrobnosti
Main Authors: Schubert, Heidi L., Phillips, John D., Heroux, Annie, Hill, Christopher P.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852885/
https://ncbi.nlm.nih.gov/pubmed/18651750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800635y
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