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Structure and Mechanistic Implications of a Uroporphyrinogen III Synthase–Product Complex,
Uroporphyrinogen III synthase (U3S) catalyzes the asymmetrical cyclization of a linear tetrapyrrole to form the physiologically relevant uroporphyrinogen III (uro’gen III) isomer during heme biosynthesis. Here, we report four apoenzyme and one product complex crystal structures of the Thermus thermo...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2852885/ https://ncbi.nlm.nih.gov/pubmed/18651750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800635y |
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