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Crystal structure of human uroporphyrinogen decarboxylase.
Uroporphyrinogen decarboxylase (URO-D) catalyzes the fifth step in the heme biosynthetic pathway, converting uroporphyrinogen to coproporphyrinogen by decarboxylating the four acetate side chains of the substrate. This activity is essential in all organisms, and subnormal activity of URO-D leads to...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170588/ https://ncbi.nlm.nih.gov/pubmed/9564029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.9.2463 |
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