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Crystal structure of human uroporphyrinogen decarboxylase.

Uroporphyrinogen decarboxylase (URO-D) catalyzes the fifth step in the heme biosynthetic pathway, converting uroporphyrinogen to coproporphyrinogen by decarboxylating the four acetate side chains of the substrate. This activity is essential in all organisms, and subnormal activity of URO-D leads to...

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Autors principals: Whitby, F G, Phillips, J D, Kushner, J P, Hill, C P
Format: Artigo
Idioma:Inglês
Publicat: 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170588/
https://ncbi.nlm.nih.gov/pubmed/9564029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.9.2463
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