Trx1 Gene Therapy Enhances Angiogenic Signaling and Reduces Ventricular Remodeling in the Infarcted Myocardium of Diabetic Rats

BACKGROUND: The present study evaluates the reversal of diabetes mediated impairment of angiogenesis in myocardial infarction (MI) model of Type I diabetic rats by intramyocardial administration of adenoviral vector encoding Thioredoxin-1 (Ad.Trx1). Various studies have linked diabetes mediated impa...

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Bibliografiset tiedot
Päätekijät: Samuel, Samson Mathews, Thirunavukkarasu, Mahesh, Penumathsa, Suresh Varma, Koneru, Srikanth, Zhan, Lijun, Maulik, Gautam, Sudhakaran, Perumana R., Maulik, Nilanjana
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852871/
https://ncbi.nlm.nih.gov/pubmed/20194885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.109.872481
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