Adeno-sh-β-Catenin Abolishes Ischemic Preconditioning–Mediated Cardioprotection by Downregulation of Its Target Genes VEGF, Bcl-2, and Survivin in Ischemic Rat Myocardium

β-Catenin, the downstream target of glycogen synthase kinase-3β (GSK-3β), plays a vital role in ischemic preconditioning (IP)-mediated cardioprotection. In the present study, we investigated the mechanism of IP-mediated cardioprotection through suppression of β-catenin expression by intramyocardial...

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Autori principali: Thirunavukkarasu, Mahesh, Han, Zhihua, Zhan, Lijun, Penumathsa, Suresh Varma, Menon, Venugopal P., Maulik, Nilanjana
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2008
Soggetti:
Original Research Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932533/
https://ncbi.nlm.nih.gov/pubmed/18407748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2008.2042
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