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Adeno-sh-β-Catenin Abolishes Ischemic Preconditioning–Mediated Cardioprotection by Downregulation of Its Target Genes VEGF, Bcl-2, and Survivin in Ischemic Rat Myocardium
β-Catenin, the downstream target of glycogen synthase kinase-3β (GSK-3β), plays a vital role in ischemic preconditioning (IP)-mediated cardioprotection. In the present study, we investigated the mechanism of IP-mediated cardioprotection through suppression of β-catenin expression by intramyocardial...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Mary Ann Liebert, Inc.
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2932533/ https://ncbi.nlm.nih.gov/pubmed/18407748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2008.2042 |
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