VEGFR1 (Flt-1(+/−)) GENE KNOCKOUT LEADS TO THE DISRUPTION OF VEGF MEDIATED SIGNALING THROUGH NITRIC OXIDE/HEMEOXYGENASE PATHWAY IN ISCHEMIC PRECONDITIONED MYOCARDIUM

This report demonstrated that mice deficient in Flt-1 failed to establish ischemic preconditioned (PC) mediated cardioprotection in isolated working buffer-perfused ischemic reperfused (IR) hearts compared to wild type (WT) subjected to same PC protocol. Wild type (WT) and Flt-1(+/−) mice were divid...

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Detalhes bibliográficos
Main Authors: Thirunavukkarasu, Mahesh, Juhasz, Bela, Zhan, Lijun, Menon, Venugopal P, Tosaki, Arpad, Otani, Hajime, Maulik, Nilanjana
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924469/
https://ncbi.nlm.nih.gov/pubmed/17448895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2007.02.011
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