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Sildenafil Augments Early Protective Transcriptional Changes After Ischemia In Mouse Myocardium

Recently, targeting cyclic-GMP specific phosphodiesterase-5 (PDE5) has attracted much interest in several cardiopulmonary diseases, in particular myocardial ischemia (MI). Although multiple mechanisms were postulated for these beneficial effects at cellular level, early transcriptional changes were...

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Detalhes bibliográficos
Main Authors: Vidavalur, Ramesh, Penumathsa, Suresh Varma, Thirunavukkarasu, Mahesh, Zhan, Lijun, Krueger, Winfried, Maulik, Nilanjana
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650511/
https://ncbi.nlm.nih.gov/pubmed/19013509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2008.10.009
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