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Sildenafil Augments Early Protective Transcriptional Changes After Ischemia In Mouse Myocardium

Recently, targeting cyclic-GMP specific phosphodiesterase-5 (PDE5) has attracted much interest in several cardiopulmonary diseases, in particular myocardial ischemia (MI). Although multiple mechanisms were postulated for these beneficial effects at cellular level, early transcriptional changes were...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Vidavalur, Ramesh, Penumathsa, Suresh Varma, Thirunavukkarasu, Mahesh, Zhan, Lijun, Krueger, Winfried, Maulik, Nilanjana
פורמט: Artigo
שפה:Inglês
יצא לאור: 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650511/
https://ncbi.nlm.nih.gov/pubmed/19013509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2008.10.009
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