Coadministration of Adenoviral Vascular Endothelial Growth Factor and Angiopoietin-1 Enhances Vascularization and Reduces Ventricular Remodeling in the Infarcted Myocardium of Type 1 Diabetic Rats

OBJECTIVE: Hyperglycemia impairs angiogenesis in response to ischemia, leading to ventricular remodeling. Although the effects of overexpressing angiogenic growth factors have been studied in inducing angiogenesis, the formation of functional vessels remains a challenge. The present study evaluates...

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Detalhes bibliográficos
Main Authors: Samuel, Samson Mathews, Akita, Yuzo, Paul, Debayon, Thirunavukkarasu, Mahesh, Zhan, Lijun, Sudhakaran, Perumana R., Li, Chuanfu, Maulik, Nilanjana
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797944/
https://ncbi.nlm.nih.gov/pubmed/19794062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0336
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