Coadministration of Adenoviral Vascular Endothelial Growth Factor and Angiopoietin-1 Enhances Vascularization and Reduces Ventricular Remodeling in the Infarcted Myocardium of Type 1 Diabetic Rats

OBJECTIVE: Hyperglycemia impairs angiogenesis in response to ischemia, leading to ventricular remodeling. Although the effects of overexpressing angiogenic growth factors have been studied in inducing angiogenesis, the formation of functional vessels remains a challenge. The present study evaluates...

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Главные авторы: Samuel, Samson Mathews, Akita, Yuzo, Paul, Debayon, Thirunavukkarasu, Mahesh, Zhan, Lijun, Sudhakaran, Perumana R., Li, Chuanfu, Maulik, Nilanjana
Формат: Artigo
Язык:Inglês
Опубликовано: American Diabetes Association 2010
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797944/
https://ncbi.nlm.nih.gov/pubmed/19794062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0336
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