Pretargeted ImmunoPET Imaging of CEA-expressing Tumors with a Bispecific Antibody and a (68)Ga- and (18)F-labeled Hapten-peptide in Mice with Human Tumor Xenografts

(18)F-Fluorodeoxyglucose ((18)F-FDG) is the most common molecular imaging agent in oncology, with a high sensitivity and specificity for detecting a number of cancers. Antibodies could enhance specificity; therefore, procedures were developed for radiolabeling a small (∼1.5 kD) hapten-peptide with (...

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Detalhes bibliográficos
Main Authors: Schoffelen, Rafke, Sharkey, Robert M., Goldenberg, David M., Franssen, Gerben, McBride, William J., Rossi, Edmund A., Chang, Chien-Hsing, Laverman, Peter, Disselhorst, Jonathan A., Eek, Annemarie, van der Graaf, Winette T.A., Oyen, Wim J.G., Boerman, Otto C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852483/
https://ncbi.nlm.nih.gov/pubmed/20354120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0862
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