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ImmunoPET Imaging of Renal Cell Carcinoma with (124)I- and (89)Zr-Labeled Anti-CAIX Monoclonal Antibody cG250 in Mice
INTRODUCTION: Monoclonal antibody (mAb) cG250 recognizes carbonic anhydrase IX (CAIX), overexpressed on clear cell renal cell carcinoma (ccRCC). (124)I-cG250 is currently under clinical investigation for the detection of ccRCC. However, the (124)I label is rapidly excreted from the tumor cells after...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Mary Ann Liebert, Inc.
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3741422/ https://ncbi.nlm.nih.gov/pubmed/23697926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cbr.2013.1487 |
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