ImmunoPET Imaging of Renal Cell Carcinoma with (124)I- and (89)Zr-Labeled Anti-CAIX Monoclonal Antibody cG250 in Mice

INTRODUCTION: Monoclonal antibody (mAb) cG250 recognizes carbonic anhydrase IX (CAIX), overexpressed on clear cell renal cell carcinoma (ccRCC). (124)I-cG250 is currently under clinical investigation for the detection of ccRCC. However, the (124)I label is rapidly excreted from the tumor cells after...

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Détails bibliographiques
Auteurs principaux: Stillebroer, Alexander B., Franssen, Gerben M., Mulders, Peter F.A., Oyen, Wim J.G., van Dongen, Guus A.M.S., Laverman, Peter, Oosterwijk, Egbert, Boerman, Otto C.
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2013
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Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741422/
https://ncbi.nlm.nih.gov/pubmed/23697926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cbr.2013.1487
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