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Shared Active Site Architecture between the Large Subunit of Eukaryotic Primase and DNA Photolyase

BACKGROUND: DNA synthesis during replication relies on RNA primers synthesised by the primase, a specialised DNA-dependent RNA polymerase that can initiate nucleic acid synthesis de novo. In archaeal and eukaryotic organisms, the primase is a heterodimeric enzyme resulting from the constitutive asso...

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Detalhes bibliográficos
Main Authors: Sauguet, Ludovic, Klinge, Sebastian, Perera, Rajika L., Maman, Joseph D., Pellegrini, Luca
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852410/
https://ncbi.nlm.nih.gov/pubmed/20404922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010083
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