Flexible tethering of primase and DNA Pol α in the eukaryotic primosome

The Pol α/primase complex or primosome is the primase/polymerase complex that initiates nucleic acid synthesis during eukaryotic replication. Within the primosome, the primase synthesizes short RNA primers that undergo limited extension by Pol α. The resulting RNA–DNA primers are utilized by Pol δ a...

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Dettagli Bibliografici
Autori principali: Núñez-Ramírez, Rafael, Klinge, Sebastian, Sauguet, Ludovic, Melero, Roberto, Recuero-Checa, María A., Kilkenny, Mairi, Perera, Rajika L., García-Alvarez, Begoña, Hall, Richard J., Nogales, Eva, Pellegrini, Luca, Llorca, Oscar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
Soggetti:
Structural Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185431/
https://ncbi.nlm.nih.gov/pubmed/21715379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr534
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