Flexible tethering of primase and DNA Pol α in the eukaryotic primosome

The Pol α/primase complex or primosome is the primase/polymerase complex that initiates nucleic acid synthesis during eukaryotic replication. Within the primosome, the primase synthesizes short RNA primers that undergo limited extension by Pol α. The resulting RNA–DNA primers are utilized by Pol δ a...

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Bibliografske podrobnosti
Main Authors: Núñez-Ramírez, Rafael, Klinge, Sebastian, Sauguet, Ludovic, Melero, Roberto, Recuero-Checa, María A., Kilkenny, Mairi, Perera, Rajika L., García-Alvarez, Begoña, Hall, Richard J., Nogales, Eva, Pellegrini, Luca, Llorca, Oscar
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2011
Teme:
Structural Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185431/
https://ncbi.nlm.nih.gov/pubmed/21715379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr534
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