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Power to detect selective allelic amplification in genome-wide scans of tumor data
Motivation: Somatic amplification of particular genomic regions and selection of cellular lineages with such amplifications drives tumor development. However, pinpointing genes under such selection has been difficult due to the large span of these regions. Our recently-developed method, the amplific...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2852215/ https://ncbi.nlm.nih.gov/pubmed/20031965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp694 |
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