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Quantifying the HIV-1 integrase inhibitor raltegravir in female genital tract secretions using high-performance liquid chromatography with ultraviolet detection

Understanding the pharmacokinetics of drugs in peripheral body compartments, such as the genital tract, is particularly important in the infectious diseases arena. However, extracting drugs from small volumes of viscous, proteinacious substances like cervicovaginal fluid is particularly challenging....

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Autors principals: Talameh, Jasmine A., Rezk, Naser L., Kashuba, Angela D.M.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852126/
https://ncbi.nlm.nih.gov/pubmed/19942487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2009.11.015
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