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An accurate and precise high performance liquid chromatography method for the rapid quantification of the novel HIV integrase inhibitor raltegravir in human blood plasma after solid phase extraction

The quantification of the HIV integrase inhibitor raltegravir in blood plasma is described using solid phase extraction (SPE) coupled with an accurate high-performance liquid chromatography assay with ultraviolet (UV) detection. The method was validated over the range of 20–10,000ng/mL using simple...

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Detalhes bibliográficos
Publicado no:Anal Chim Acta
Main Authors: Rezk, Naser L., White, Nicole, Kashuba, Angela D.M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480778/
https://ncbi.nlm.nih.gov/pubmed/18929009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.aca.2008.09.007
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