Selective and rapid determination of raltegravir in human plasma by liquid chromatography–tandem mass spectrometry in the negative ionization mode

A selective and rapid high-performance liquid chromatography–tandem mass spectrometry method was developed and validated for the quantification of raltegravir using raltegravir-d3 as an internal standard (IS). The analyte and IS were extracted with methylene chloride and n-hexane solvent mixture fro...

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Veröffentlicht in:J Pharm Anal
Hauptverfasser: Gupta, Ajay, Guttikar, Swati, Shah, Priyanka A., Solanki, Gajendra, Shrivastav, Pranav S., Sanyal, Mallika
Format: Artigo
Sprache:Inglês
Veröffentlicht: Xi'an Jiaotong University 2015
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5761471/
https://ncbi.nlm.nih.gov/pubmed/29403921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2014.10.002
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