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Quantifying the HIV-1 integrase inhibitor raltegravir in female genital tract secretions using high-performance liquid chromatography with ultraviolet detection

Understanding the pharmacokinetics of drugs in peripheral body compartments, such as the genital tract, is particularly important in the infectious diseases arena. However, extracting drugs from small volumes of viscous, proteinacious substances like cervicovaginal fluid is particularly challenging....

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Detalhes bibliográficos
Main Authors: Talameh, Jasmine A., Rezk, Naser L., Kashuba, Angela D.M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852126/
https://ncbi.nlm.nih.gov/pubmed/19942487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2009.11.015
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