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Mechanisms of acute axonal degeneration in the optic nerve in vivo

Axonal degeneration is an initial key step in traumatic and neurodegenerative CNS disorders. We established a unique in vivo epifluorescence imaging paradigm to characterize very early events in axonal degeneration in the rat optic nerve. Single retinal ganglion cell axons were visualized by AAV-med...

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Détails bibliographiques
Auteurs principaux: Knöferle, Johanna, Koch, Jan C., Ostendorf, Thomas, Michel, Uwe, Planchamp, Véronique, Vutova, Polya, Tönges, Lars, Stadelmann, Christine, Brück, Wolfgang, Bähr, Mathias, Lingor, Paul
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851885/
https://ncbi.nlm.nih.gov/pubmed/20231460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909794107
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