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The Mycobacterium tuberculosis gene, ldt(Mt2), encodes a non-classical transpeptidase required for virulence and resistance to amoxicillin

The peptidoglycan layer is a vital component of the bacterial cell wall. The existing paradigm describes the peptidoglycan network as a static structure that is cross-linked predominantly by 4→3 transpeptide linkages. However, the non-classical 3→3 linkages predominate the transpeptide networking of...

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Detalhes bibliográficos
Main Authors: Gupta, Radhika, Lavollay, Marie, Mainardi, Jean-Luc, Arthur, Michel, Bishai, William R., Lamichhane, Gyanu
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851841/
https://ncbi.nlm.nih.gov/pubmed/20305661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2120
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