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Hydrophobically stabilized open state for the lateral gate of the Sec translocon
The Sec translocon is a central component of cellular pathways for protein translocation and membrane integration. Using both atomistic and coarse-grained molecular simulations, we investigate the conformational landscape of the translocon and explore the role of peptide substrates in the regulation...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851780/ https://ncbi.nlm.nih.gov/pubmed/20203009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914752107 |
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