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Hydrophobically stabilized open state for the lateral gate of the Sec translocon

The Sec translocon is a central component of cellular pathways for protein translocation and membrane integration. Using both atomistic and coarse-grained molecular simulations, we investigate the conformational landscape of the translocon and explore the role of peptide substrates in the regulation...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhang, Bin, Miller, Thomas F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851780/
https://ncbi.nlm.nih.gov/pubmed/20203009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914752107
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