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Characterization of somatic cell nuclear reprogramming by oocytes in which a linker histone is required for pluripotency gene reactivation

When transplanted into Xenopus oocytes, the nuclei of mammalian somatic cells are reprogrammed to express stem cell genes such as Oct4, Nanog, and Sox2. We now describe an experimental system in which the pluripotency genes Sox2 and Oct4 are repressed in retinoic acid-treated ES cells but are reprog...

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Autori principali: Jullien, Jerome, Åstrand, Carolina, Halley-Stott, Richard P., Garrett, Nigel, Gurdon, John B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851752/
https://ncbi.nlm.nih.gov/pubmed/20212135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000599107
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