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Characterization of somatic cell nuclear reprogramming by oocytes in which a linker histone is required for pluripotency gene reactivation

When transplanted into Xenopus oocytes, the nuclei of mammalian somatic cells are reprogrammed to express stem cell genes such as Oct4, Nanog, and Sox2. We now describe an experimental system in which the pluripotency genes Sox2 and Oct4 are repressed in retinoic acid-treated ES cells but are reprog...

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Hlavní autoři: Jullien, Jerome, Åstrand, Carolina, Halley-Stott, Richard P., Garrett, Nigel, Gurdon, John B.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851752/
https://ncbi.nlm.nih.gov/pubmed/20212135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000599107
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