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Force-Induced Bidirectional Stepping of Cytoplasmic Dynein
Cytoplasmic dynein is a minus-end-directed microtubule motor whose mechanism of movement remains poorly understood. Here, we use optical tweezers to examine the force-dependent stepping behavior of yeast cytoplasmic dynein. We find that dynein primarily advances in 8 nm increments but takes other si...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851641/ https://ncbi.nlm.nih.gov/pubmed/18045537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.10.016 |
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