Single-Molecule Analysis of Dynein Processivity and Stepping Behavior

Cytoplasmic dynein, the 1.2 MDa motor driving minus-end-directed motility, has been reported to move processively along microtubules, but its mechanism of motility remains poorly understood. Here, using S. cerevisiae to produce recombinant dynein with a chemically controlled dimerization switch, we...

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Main Authors: Reck-Peterson, Samara L., Yildiz, Ahmet, Carter, Andrew P., Gennerich, Arne, Zhang, Nan, Vale, Ronald D.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851639/
https://ncbi.nlm.nih.gov/pubmed/16873064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.05.046
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