Llwytho...
Paclitaxel promotes a caspase 8-mediated apoptosis via death effector domain association with microtubules
Microtubule-perturbing drugs have become front line chemotherapeutics, inducing cell cycle crisis as a major mechanism of action. However, these agents exhibit pleiotropic effects on cells, and can induce apoptosis via other means. Paclitaxel, a microtubule-stabilizing agent, induces a caspase-depen...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2009
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851247/ https://ncbi.nlm.nih.gov/pubmed/19668227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.210 |
| Tagiau: |
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