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The Death Effector Domains of Caspase-8 Induce Terminal Differentiation

The differentiation and senescence programs of metazoans play key roles in regulating normal development and preventing aberrant cell proliferation, such as cancer. These programs are intimately associated with both the mitotic and apoptotic pathways. Caspase-8 is an apical apoptotic initiator that...

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Detalhes bibliográficos
Main Authors: Mielgo, Ainhoa, Torres, Vicente A., Schmid, Michael C., Graf, Ryon, Zeitlin, Samantha G., Lee, Pedro, Shields, David J., Barbero, Simone, Jamora, Colin, Stupack, Dwayne G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774162/
https://ncbi.nlm.nih.gov/pubmed/19924290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007879
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