The Death Effector Domains of Caspase-8 Induce Terminal Differentiation

The differentiation and senescence programs of metazoans play key roles in regulating normal development and preventing aberrant cell proliferation, such as cancer. These programs are intimately associated with both the mitotic and apoptotic pathways. Caspase-8 is an apical apoptotic initiator that...

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Main Authors: Mielgo, Ainhoa, Torres, Vicente A., Schmid, Michael C., Graf, Ryon, Zeitlin, Samantha G., Lee, Pedro, Shields, David J., Barbero, Simone, Jamora, Colin, Stupack, Dwayne G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2009
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774162/
https://ncbi.nlm.nih.gov/pubmed/19924290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007879
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