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Identification of a Critical Tyrosine Residue in Caspase 8 That Promotes Cell Migration
Caspase 8 is a critical upstream initiator of programmed cell death but, paradoxically, has also been shown to promote cell migration. Here, we show that tyrosine 380 in the linker loop of human caspase 8 is a critical switch determining caspase 8 function. Our studies show that, in addition to its...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2442311/ https://ncbi.nlm.nih.gov/pubmed/18216014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800549200 |
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