Caspase 8 association with the focal adhesion complex promotes tumor cell migration and metastasis

Caspase 8 (Casp-8) is a proapoptotic protease which suppresses neuroblastoma metastasis by inducing programmed cell death. Paradoxically, Casp-8 can also promote cell migration among nonapoptotic cells, and here we show that Casp-8 can promote metastasis when apoptosis is compromised. Migration is e...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Barbero, Simone, Mielgo, Ainhoa, Torres, Vicente, Teitz, Tal, Shields, David J., Mikolon, David, Bogyo, Matthew, Barilà, Daniela, Lahti, Jill M., Schlaepfer, David, Stupack, Dwayne G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684981/
https://ncbi.nlm.nih.gov/pubmed/19383910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3937
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg