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Caspase 8 association with the focal adhesion complex promotes tumor cell migration and metastasis
Caspase 8 (Casp-8) is a proapoptotic protease which suppresses neuroblastoma metastasis by inducing programmed cell death. Paradoxically, Casp-8 can also promote cell migration among nonapoptotic cells, and here we show that Casp-8 can promote metastasis when apoptosis is compromised. Migration is e...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2684981/ https://ncbi.nlm.nih.gov/pubmed/19383910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3937 |
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