Загрузка...
Inhibition of Human Arginase I by Substrate and Product Analogues
Human arginase I is a binuclear manganese metalloenzyme that catalyzes the hydrolysis of L-arginine to generate L-ornithine and urea. We demonstrate that N-hydroxy-L-arginine (NOHA) binds to this enzyme with K(d) = 3.6 μM, and nor-N-hydroxy-L-arginine (nor-NOHA) binds with K(d) = 517 nM (surface pla...
Сохранить в:
| Главные авторы: | , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2850953/ https://ncbi.nlm.nih.gov/pubmed/20153713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2010.02.004 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|