Nalaganje...
Cysteine 95 and other residues influence the regulatory effects of Histidine 69 mutations on Human Immunodeficiency Virus Type 1 protease autoprocessing
BACKGROUND: Regulated autoprocessing of HIV Gag-Pol precursor is required for the production of mature and fully active protease. We previously reported that H69E mutation in a pseudo wild type protease sequence significantly (>20-fold) impedes protease maturation in an in vitro autoprocessing as...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2010
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2850873/ https://ncbi.nlm.nih.gov/pubmed/20331855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-7-24 |
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