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Modulation of Human Immunodeficiency Virus Type 1 Protease Autoprocessing by Charge Properties of Surface Residue 69

Mature, fully active human immunodeficiency virus protease (PR) is liberated from the Gag-Pol precursor via regulated autoprocessing. A chimeric protease precursor, glutathione S-transferase-transframe region (TFR)-PR-FLAG, also undergoes N-terminal autocatalytic maturation when it is expressed in E...

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Detalles Bibliográficos
Main Authors: Huang, Liangqun, Sayer, Jane M., Swinford, Marie, Louis, John M., Chen, Chaoping
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708634/
https://ncbi.nlm.nih.gov/pubmed/19457992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00473-09
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