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Understanding HIV-1 protease autoprocessing for novel therapeutic development
In the infected cell, HIV-1 protease (PR) is initially synthesized as part of the GagPol polyprotein. PR autoprocessing is a virus-specific process by which the PR domain embedded in the precursor catalyzes proteolytic reactions responsible for liberation of free mature PRs, which then recognize and...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3826259/ https://ncbi.nlm.nih.gov/pubmed/23859204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.13.89 |
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