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CyDNA: Synthesis and Replication of Highly Cy-Dye Substituted DNA by an Evolved Polymerase

[Image: see text] DNA not only transmits genetic information but can also serve as a versatile supramolecular scaffold. Here we describe a strategy for the synthesis and replication of DNA displaying hundreds of substituents using directed evolution of polymerase function by short-patch compartmenta...

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Detalhes bibliográficos
Main Authors: Ramsay, Nicola, Jemth, Ann-Sofie, Brown, Anthony, Crampton, Neal, Dear, Paul, Holliger, Philipp
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2010
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850551/
https://ncbi.nlm.nih.gov/pubmed/20235594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja909180c
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