Fibril fragmentation in amyloid assembly and cytotoxicity: When size matters

Amyloid assemblies are associated with several debilitating human disorders. Understanding the intra- and extracellular assembly of normally soluble proteins and peptides into amyloid aggregates and how they disrupt normal cellular functions is therefore of paramount importance. In a recent report,...

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Huvudupphovsmän: Xue, Wei-Feng, Hellewell, Andrew L, Hewitt, Eric W, Radford, Sheena E
Materialtyp: Artigo
Språk:Inglês
Publicerad: Landes Bioscience 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850416/
https://ncbi.nlm.nih.gov/pubmed/20305394
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