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An Imaging and Systems Modeling Approach to Fibril Breakage Enables Prediction of Amyloid Behavior

Delineating the nanoscale properties and the dynamic assembly and disassembly behaviors of amyloid fibrils is key for technological applications that use the material properties of amyloid fibrils, as well as for developing treatments of amyloid-associated disease. However, quantitative mechanistic...

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Bibliographic Details
Main Authors: Xue, Wei-Feng, Radford, Sheena E.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882454/
https://ncbi.nlm.nih.gov/pubmed/24359753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.10.034
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