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Modulation of β-Amyloid Fibril Formation in Alzheimer’s Disease by Microglia and Infection

Amyloid plaques are a pathological hallmark of Alzheimer’s disease. The major component of these plaques are highly ordered amyloid fibrils formed by amyloid-β (Aβ) peptides. However, whilst Aβ amyloid fibril assembly has been subjected to detailed and extensive analysis in vitro, these studies may...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Brown, Madeleine R., Radford, Sheena E., Hewitt, Eric W.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725705/
https://ncbi.nlm.nih.gov/pubmed/33324164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2020.609073
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