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Increased O-GlcNAc levels during reperfusion leads to improved functional recovery and reduced calpain-proteolysis

We have previously shown that pre-ischemic treatment with glucosamine improved cardiac functional recovery following ischemia/reperfusion (I/R) and this was mediated, at least in part, via enhanced flux through the hexosamine biosynthesis pathway (HBP) and subsequently elevated protein O-GlcNAc leve...

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Detalhes bibliográficos
Main Authors: Liu, Jia, Marchase, Richard B., Chatham, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850209/
https://ncbi.nlm.nih.gov/pubmed/17573462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00285.2007
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