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Glutamine-induced protection of isolated rat heart from ischemia/reperfusion injury is mediated via the hexosamine biosynthesis pathway and increased protein O-GlcNAc levels

It has been shown that glutamine protects the heart from ischemia/reperfusion (I/R) injury; however, the mechanisms underlying this protection have not been identfied. Glutamine: fructose-6-phosphate amidotransferase (GFAT) regulates the entry of glucose into the hexosamine biosynthesis pathway (HBP...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Liu, Jia, Marchase, Richard B., Chatham, John C.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2006
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779903/
https://ncbi.nlm.nih.gov/pubmed/17069847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2006.09.015
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