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The Hexosamine Signaling Pathway: O-GlcNAc cycling in feast or famine

The enzymes of O-GlcNAc cycling couple the nutrient-dependent synthesis of UDP-GlcNAc to O-GlcNAc modification of Ser/Thr residues of key nuclear and cytoplasmic targets. This series of reactions culminating in O-GlcNAcylation of targets has been termed the Hexosamine Signaling Pathway (HSP). The ev...

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Hlavní autoři: Hanover, John A., Krause, Michael W., Love, Dona C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815088/
https://ncbi.nlm.nih.gov/pubmed/19647043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2009.07.017
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