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The Hexosamine Signaling Pathway: O-GlcNAc cycling in feast or famine
The enzymes of O-GlcNAc cycling couple the nutrient-dependent synthesis of UDP-GlcNAc to O-GlcNAc modification of Ser/Thr residues of key nuclear and cytoplasmic targets. This series of reactions culminating in O-GlcNAcylation of targets has been termed the Hexosamine Signaling Pathway (HSP). The ev...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2815088/ https://ncbi.nlm.nih.gov/pubmed/19647043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2009.07.017 |
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