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O-GlcNAc cycling: Emerging Roles in Development and Epigenetics
The nutrient-sensing hexosamine signaling pathway modulates the levels of O-linked N-acetylglucosamine (O-GlcNAc) on key targets impacting cellular signaling, protein turnover and gene expression. O-GlcNAc cycling may be deregulated in neurodegenerative disease, cancer, and diabetes. Studies in mode...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2917487/ https://ncbi.nlm.nih.gov/pubmed/20488252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2010.05.001 |
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