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c-Jun Controls the Ability of IL-12 to Induce IL-10 Production from Human Memory CD4(+) T Cells

IL-12p70 is an immunoregulatory cytokine that has been shown to induce IL-10 production from CD4(+) T cells, yet the underlying cellular mechanisms controlling this process are poorly understood. In the present study, we demonstrate that IL-12p70 induces IL-10 production from human memory CD4(+) T c...

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Autors principals: Garcia, Carlos A., Wang, Huizhi, Benakanakere, Manjunatha R., Barrett, Elyse, Kinane, Denis F., Martin, Michael
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849968/
https://ncbi.nlm.nih.gov/pubmed/19734233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901283
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