Interleukin 18 Coexpression during Respiratory Syncytial Virus Infection Results in Enhanced Disease Mediated by Natural Killer Cells

Respiratory syncytial virus (RSV) causes bronchiolitis, the main cause of infantile hospitalization. Immunity against reinfection is poor, and there is great interest in boosting vaccine responses using live vectors expressing host cytokines. We therefore constructed a recombinant RSV expressing mur...

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Bibliografski detalji
Glavni autori: Harker, James A., Godlee, Alexandra, Wahlsten, Jennifer L., Lee, Debbie C. P., Thorne, Lucy G., Sawant, Devika, Tregoning, John S., Caspi, Rachel R., Bukreyev, Alexander, Collins, Peter L., Openshaw, Peter J. M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Pathogenesis and Immunity
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849516/
https://ncbi.nlm.nih.gov/pubmed/20130064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02014-09
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