Delivery of Cytokines by Recombinant Virus in Early Life Alters the Immune Response to Adult Lung Infection

Respiratory syncytial virus (RSV) is the main cause of bronchiolitis, the major cause of hospitalization of infants. An ideal RSV vaccine would be effective for neonates, but the immune responses of infants differ markedly from those of adults, often showing a bias toward T-helper 2 (Th2) responses...

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Bibliographische Detailangaben
Hauptverfasser: Harker, James A., Lee, Debbie C. P., Yamaguchi, Yuko, Wang, Belinda, Bukreyev, Alexander, Collins, Peter L., Tregoning, John S., Openshaw, Peter J. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863826/
https://ncbi.nlm.nih.gov/pubmed/20200251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02503-09
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