Delivery of Cytokines by Recombinant Virus in Early Life Alters the Immune Response to Adult Lung Infection

Respiratory syncytial virus (RSV) is the main cause of bronchiolitis, the major cause of hospitalization of infants. An ideal RSV vaccine would be effective for neonates, but the immune responses of infants differ markedly from those of adults, often showing a bias toward T-helper 2 (Th2) responses...

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Detalhes bibliográficos
Main Authors: Harker, James A., Lee, Debbie C. P., Yamaguchi, Yuko, Wang, Belinda, Bukreyev, Alexander, Collins, Peter L., Tregoning, John S., Openshaw, Peter J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863826/
https://ncbi.nlm.nih.gov/pubmed/20200251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02503-09
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