Interleukin 18 Coexpression during Respiratory Syncytial Virus Infection Results in Enhanced Disease Mediated by Natural Killer Cells

Respiratory syncytial virus (RSV) causes bronchiolitis, the main cause of infantile hospitalization. Immunity against reinfection is poor, and there is great interest in boosting vaccine responses using live vectors expressing host cytokines. We therefore constructed a recombinant RSV expressing mur...

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Detalhes bibliográficos
Main Authors: Harker, James A., Godlee, Alexandra, Wahlsten, Jennifer L., Lee, Debbie C. P., Thorne, Lucy G., Sawant, Devika, Tregoning, John S., Caspi, Rachel R., Bukreyev, Alexander, Collins, Peter L., Openshaw, Peter J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849516/
https://ncbi.nlm.nih.gov/pubmed/20130064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02014-09
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