Inhibition of Herpes Simplex Virus Type 1 Replication by Adeno-Associated Virus Rep Proteins Depends on Their Combined DNA-Binding and ATPase/Helicase Activities

Adeno-associated virus (AAV) has previously been shown to inhibit the replication of its helper virus herpes simplex virus type 1 (HSV-1), and the inhibitory activity has been attributed to the expression of the AAV Rep proteins. In the present study, we assessed the Rep activities required for inhi...

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Hauptverfasser: Glauser, Daniel L., Seyffert, Michael, Strasser, Regina, Franchini, Marco, Laimbacher, Andrea S., Dresch, Christiane, de Oliveira, Anna Paula, Vogel, Rebecca, Büning, Hildegard, Salvetti, Anna, Ackermann, Mathias, Fraefel, Cornel
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Genome Replication and Regulation of Viral Gene Expression
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849494/
https://ncbi.nlm.nih.gov/pubmed/20106923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01503-09
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