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Kinetics of Hedgehog-Dependent Full-Length Gli3 Accumulation in Primary Cilia and Subsequent Degradation

Hedgehog (Hh) signaling in vertebrates depends on intraflagellar transport (IFT) within primary cilia. The Hh receptor Patched is found in cilia in the absence of Hh and is replaced by the signal transducer Smoothened within an hour of Hh stimulation. By generating antibodies capable of detecting en...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Wen, Xiaohui, Lai, Cary K., Evangelista, Marie, Hongo, Jo-Anne, de Sauvage, Frederic J., Scales, Suzie J.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849461/
https://ncbi.nlm.nih.gov/pubmed/20154143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01089-09
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