Coincorporation of LpxL1 and PagL Mutant Lipopolysaccharides into Liposomes with Neisseria meningitidis Opacity Protein: Influence on Endotoxic and Adjuvant Activity

Wild-type lipopolysaccharide (LPS) of Neisseria meningitidis normally contains six acyl chains. Penta-acylated LPS forms were generated through inactivation of the lpxL1 gene or through the expression of the Bordetella bronchiseptica pagL gene in N. meningitidis. The resulting LPS species, designate...

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Autores principales: Arenas, Jesús, van Dijken, Harry, Kuipers, Betsy, Hamstra, Hendrik Jan, Tommassen, Jan, van der Ley, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Materias:
Immune Mechanisms
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849350/
https://ncbi.nlm.nih.gov/pubmed/20107001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00423-09
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